In June 2013, the WHO released consolidated guidelines on the use of antiretrovirals (ARVs) . The launch of these new guidelines is another milestone in the global endeavor toward universal access to antiretroviral treatment (ART) using the public health approach, pursuing the dual advantage of ...

By the end of 2012, the number of people receiving antiretroviral treatment (ART) in low and middle-income countries reached 9.7 million, including 7.2 million in sub-Saharan Africa. The bad news is that these figures represent only 65% of the global target of 15 million people ...

Objective: To determine the status of key national policies on the use of antiretroviral therapy (ART) at the time of the launch of the 2013 WHO consolidated guidelines as well as to track early progress towards adoption of these recommendations following dissemination. Design: Descriptive analysis of ...

Mental Health Gap Action Programme (mhGAP) – background About four out of five people in low- and middle-income countries who need services for mental, neurological and substance use conditions do not receive them. Even when available, the interventions often are neither evidence-based nor of high quality. ...

Revisions to the April 8, 2015, version of the guidelines are largely based on findings from two large, randomized controlled trials that addressed the optimal time to initiate antiretroviral therapy (ART)—START (Strategic Timing of Antiretroviral Therapy) and TEMPRANO. Both studies demonstrated approximately a 50% reduction ...

The Prequalification of Medicines Programme (PQP) • A United Nations Programme managed by WHO • Started in March 2001 as a Pilot Project: Focus on HIV/AIDS • Partners included WHO, UNICEF, UNFPA, UNAIDS and supported by World Bank • Quickly expanded to include Tuberculosis, Malaria, Reproductive Health, Influenza and ...

PEPFAR’s Evolution. From Emergency Response to Sustainable Impact for an AIDS-free Generation. 2003-2007: PEPFAR 1 Emergency Response Delivering prevention, care and treatment services Building and strengthening health systems to deliver HIV services 2008-2012: PEPFAR 2 Shift to sustainable response Shared responsibility and country driven programs Scaling up core interventions (ART, PMTCT, and VMMC) ...

Purpose of the new PQ financing strategy: • Maintain the overall objective of PQ to provide assured safe, efficacious and quality drugs, vaccines, diagnostics and devices while increasing supply and access; • Need for an innovative, practical and sustainable funding approach for the WHO PQ programme; • Reduce ...

Currently does not include estimates of number of people who may need PrEP (e.g. number of IDUs at high risk of HIV acquisition) or TasP • Borrows average usage forecast from currently available forecasts till 2018 • Borrows epidemiological estimates from available estimates till 2018 • Assumptions: – Linear ...

Background: Extent and timing of public health usage of ARVs, especially new drugs, was a key area for the MPP to understand when we commenced our licensing work with originator and generic companies • MPP started its forecasting exercise in 2011, including all ARVs but focusing on ...

WHO/UNAIDS Consultation with manufacturers. March 2015, Geneva, Switzerland Key Points • The IATT Optimal Formulary is designed to guide selection and procurement of paediatric ARV’s around a subset of optimal products • Consolidation of demand stabilizes supplies of paediatric ARVs • Success requires global consensus, cooperation with the manufacturers, ...

Forecasting demand for ARV's trends of pediatric formularions uptake from the GPRM Database

Update on the Global Fund’s Procurement Strategy. WHO UNAIDS Annual Meeting with Pharmaceutical Stakeholders Key outcomes The long term collaborative agreements will support continuous supply through improved lead times and better delivery performance Supply risks mitigated with multiple awardees per product and diversification of API sources ...