Hepatitis C genotype 4 combination therapy found to be safe and effective

Researchers recently published their findings on a combination therapy for use in patients with hepatitis C (HCV) genotype 4 in PLoS One. According to the Belgian researchers, sofosbuvir in combination with simeprevir with or without ribarivirn was found to be safe and effective. According to the ...

February 07, 2017
EATG  News  

Regulus announces continuation of RG-101 clinical hold

Regulus Therapeutics Inc. (Nasdaq: RGLS), a biopharmaceutical company leading the discovery and development of innovative medicines targeting microRNAs, today announced that it received written communication from the U.S. Food and Drug Administration (FDA) that the clinical development program for RG-101 remains on clinical hold. In ...

January 31, 2017
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EUPATI All Aboard to a Better Health Future – presentations online

On December 14 2016, the closing EUPATI workshop named “All Aboard to a Better Health Future” took place in Brussels. The meeting presented the achievements, learnings, goals, work done, accomplishments, as well as plans for the future sustainability and continuation of the EUPATI toolbox, trainings, ...

January 31, 2017

Final yes from NICE for Gilead’s Epclusa

The National Institute for Health and Care Excellence has now published final guidance endorsing Epclusa as an option for the treatment of adults with chronic hepatitis C genotype 1-6 infection on the NHS in England and Wales. Epclusa – a once-daily, fixed-dose combination of the nucleotide ...

January 27, 2017
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Alliance starts treating hepatitis C with the combination of sofosbuvir/ledipasvir

Currently most effective directly-acting antiviral agent for hepatitis C (HCV) treatment has already arrived to Ukraine! Alliance for Public Health launches the third phase of HCV treatment program for key populations. This phase stipulates using a direct-acting antiviral agent, which is new for Ukraine – Harvoni ...

January 26, 2017
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Medicines Patent Pool announces first licence for TB treatment

In an effort to improve the international response to combatting multidrug-resistant TB, MPP and Johns Hopkins University sign licensing agreement for investigational treatment sutezolid Geneva, 25 January 2017 — The Medicines Patent Pool today announced that it has signed a licence with Johns Hopkins University ...

January 26, 2017
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Cognitive decline in hepatitis C could be influenced by interferon treatment

A group of researchers is investigating whether or not interferon-free therapy could reverse the cognitive declines that appear to accompany infection with the hepatitis C virus (HCV), with or HIV coinfection. Felix Kleefeld, of Berlin, Germany, and colleagues examined how eradicating HCV affected the cognition of ...

January 24, 2017
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Immediate ART for HIV protects against severe bacterial infections

Initiating, rather than deferring, antiretroviral therapy (ART) reduces the risk of severe bacterial infections in HIV-positive individuals with high CD4 counts, researchers say. Their data are from the START trial, which showed a 57% reduction in the risk of AIDS and non-AIDS morbidity and mortality in ...

January 24, 2017
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Uzbekistan: Pioneering clinical trial for drug-resistant TB starts

A pioneering new clinical trial aiming to find a radically improved course of treatment for drug-resistant tuberculosis (TB) began on 17th January 2017, when the first patient took the first pill in Uzbekistan. The phase II/III trial, called TB PRACTECAL, aims to find a treatment regime ...

January 24, 2017
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