New and touted HIV bNAb: Big deal or news blip?

Fervid research has uncovered dozens of antibodies that shield cells from HIV. These broadly neutralizing antibodies (bNAbs) protect monkeys from SHIV, the simian-HIV hybrid. Thousand-person human trials are already dripping bNAbs into high-risk men and women to see if they prevent HIV infection. And much ...

January 26, 2017
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Antibody combination puts HIV on the ropes

Without antiretroviral drug treatment, the majority of people infected with HIV ultimately develop AIDS, as the virus changes and evolves beyond the body’s ability to control it. But a small group of infected individuals—called elite controllers—possess immune systems capable of defeating the virus. They accomplish ...

January 26, 2017
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Gene therapy to cure HIV: Where to from here?

Gene therapy — which involves modifying genetic material, such as DNA and RNA — holds exciting potential as a cure for numerous diseases and conditions, including HIV. Timothy Brown (the “Berlin patient”) remains the only person known to have been cured of HIV. Brown received a ...

January 25, 2017
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Cognitive decline in hepatitis C could be influenced by interferon treatment

A group of researchers is investigating whether or not interferon-free therapy could reverse the cognitive declines that appear to accompany infection with the hepatitis C virus (HCV), with or HIV coinfection. Felix Kleefeld, of Berlin, Germany, and colleagues examined how eradicating HCV affected the cognition of ...

January 24, 2017
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Uzbekistan: Pioneering clinical trial for drug-resistant TB starts

A pioneering new clinical trial aiming to find a radically improved course of treatment for drug-resistant tuberculosis (TB) began on 17th January 2017, when the first patient took the first pill in Uzbekistan. The phase II/III trial, called TB PRACTECAL, aims to find a treatment regime ...

January 24, 2017
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Antibody breakthroughs give new hope for HIV treatment

Researchers in two new studies say they can leverage the body’s own antibodies to fight the virus that causes AIDS. In the field of HIV research, antibodies continue to be a targeted area. Two new studies published January 19 in Science Translational Medicine offer potential new treatment ...

January 24, 2017
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Man successfully receives first hepatitis C-infected liver transplant

For the first time in the United States, a 31-year-old male with primary sclerosing cholangitis received a liver transplant from a deceased donor infected with hepatitis C virus (HCV). Primary sclerosis cholangitis slowly damages the bile ducts in the liver. After Lorenzo Swank learned his liver ...

January 24, 2017
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Opportunities for addiction care and HIV prevention in Russia

Agonist therapy with methadone could use existing structure to reduce addiction, HIV Opioid agonist therapy using methadone is regarded as one of the most effective treatments for opioid use disorders as well as helping to reduce HIV risks. Such therapy, however, is not yet available in ...

January 24, 2017
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GeoVax announces initiation of HIV human clinical trial

GeoVax Labs, Inc. (OTCQB: GOVX), a biotechnology company developing human vaccines, announced today (January 23) the initiation of the next human clinical trial of GeoVax’s preventive HIV vaccine, GOVX-B11. The Phase 1 trial (designated HVTN 114) is being conducted by the HIV Vaccine Trials Network ...

January 24, 2017
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Managing HIV in the aging population

Long-term care for an aging HIV population is uncharted territory, as researchers and physicians are seeing the effects of the first wave of individuals who have been on antiretroviral therapy (ART) for a significant period of time. An increasing amount of academic and clinical research has ...

January 23, 2017
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GeoVax to collaborate with Georgia State University on development of therapeutic hepatitis B vaccine

Targeting chronic hepatitis B infections affecting more than 240 million people worldwide GeoVax Labs, Inc. (OTCQB: GOVX), a biotechnology company developing human vaccines, announced today (January 17) that it has entered into a research collaboration agreement with Georgia State University Research Foundation (GSU) to advance the ...

January 23, 2017
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Successful antibody trial in HIV-infected individuals

A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research (DZIF), has tested a new HIV neutralising antibody, called 10-1074, in humans. The results of the trial have just ...

January 19, 2017