A research team led by investigators of the Rockefeller University in New York and Prof Florian Klein, University Hospital Cologne and German Center for Infection Research (DZIF), has tested a new HIV neutralising antibody, called 10-1074, in humans. The results of the trial have just ...

Prohibition can prevent access to harm reduction treatment, including methadone, for people who inject drugs, writes Michel Kazatchkine Why is eastern Europe the only region in the world that still has a growing HIV epidemic?1 In one of the region’s countries, Russia, more than two thirds ...

The antiretroviral drugs used to treat HIV infection might inadvertently be boosting gay/bisexual men’s susceptibility to the bacteria responsible for syphilis, Treponema pallidum, conclude researchers in the journal Sexually Transmitted Infections. This might explain why new and repeat cases in these groups have risen so sharply ...

Great advances in science often come from outside the direct field of research. Since the early days of the epidemic, the HIV research community brought together clinicians, virologists, social scientists, and community members to try to shed light on the devastating disease. More than 30 years ...

The vast majority of people taking antiretroviral therapy (ART) in the UK have an accurate knowledge of their current viral load (VL) level, investigators report in HIV Medicine. Overall, 96% of people who told researchers their viral load was undetectable had a clinic-recorded viral load ...

There are a number of things that can impact our immune system’s ability to eliminate a virus; the expression levels of particular proteins—specifically interferon proteins—is one of them. In the past, human type I interferons (IFNs), a large subgroup of interferon proteins, were thought to ...

Supplement to consolidated guidelines on HIV testing services Since the release of the consolidated guidelines in 2015, new evidence has emerged. Consequently, in an effort to further support countries, programme managers, health workers and other stakeholders seeking to achieve national and international HIV goals, this 2016 ...

The January issue of the Journal includes papers on a range of topics and reports from two recent meetings – the Ghent HIV Reservoir Characterization Symposium and the Third Biennial Strategies for an HIV Cure Meeting. To read an overview of the issue, click here. The January ...

Last month’s announcement that the Bill and Melinda Gates Foundation will give up to $140 million to a Boston drug device manufacturer to develop an implantable mini-pump to deliver drugs for pre-exposure prophylaxis (PrEP) against HIV infection has focused attention on the future of PrEP. ...

People living with HIV often worry about whether HIV is accelerating the aging process. HIV itself isn’t making many people ill, but some people with HIV are having problems with heart disease, cancers and brittle bones. These conditions — typically experienced as people get older ...

Dramatic decrease of funding from donors for HIV and TB responses and inability or unwillingness of governments to finance such programs has devastating effects on key affected populations (KAPs) in middle-income countries (MICs) – sex workers, men who have sex with men, people who use ...

A risk score based on routine assessments carried out during antenatal care in resource-limited settings can accurately predict which pregnant and breastfeeding women have an especially high risk of infection with HIV and would therefore benefit from pre-exposure prophylaxis (PrEP), investigators report in the online ...

Risk calculator developed by UCLA and Los Angeles LGBT Center may fill that void A new study from the UCLA Fielding School of Public Health suggests modifying federal health guidelines related to the use of pre-exposure prophylaxis to prevent HIV transmission because current standards could miss ...

Retroviruses – the family of viruses that includes HIV – are almost half a billion years old, according to new research by scientists at Oxford University. That’s several hundred million years older than previously thought and suggests retroviruses have ancient marine origins, having been with ...

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 218: Research with women and HIV, December 2016 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-218 Original Article

Antiviral therapy could be improved with the newly uncovered atomic-level details LA JOLLA—Salk Institute scientists have solved the atomic structure of a key piece of machinery that allows HIV to integrate into human host DNA and replicate in the body, which has eluded researchers for decades. ...

Study identifies characteristics of HIV-1 strains that mediate sexual transmission PHILADELPHIA – Upon sexual exposure, the AIDS virus must overcome some mighty barriers to find the right target cell and establish a new infection. It must traverse the genital mucosa and squeeze through tightly packed epithelial ...

Smoking “dramatically” increases the risk of pregnancy loss – miscarriage or stillbirth – in HIV-positive women, US investigators report in the online edition of AIDS. Researchers from the large Women’s Interagency HIV Study (WIHS) examined the impact of smoking on pregnancy loss in HIV-positive and ...