A dual antiretroviral regimen containing dolutegravir (Tivicay) and boosted darunavir (Prezista) maintains viral suppression in most people who switch from a suppressive three-drug regimen, according to an observational study presented at the recent IDWeek in San Francisco. However, two drugs may not be enough for ...

Using dolutegravir alone, as maintenance treatment after achieving undetectable viral load on a three-drug regimen, results in an unacceptable rate of viral rebound and is unethical in the view of many experts, the 22nd International AIDS Conference (AIDS 2018) heard last month.

Safety concern over dolutegravir use in early pregnancy highlights limited contraception choices for many women living with HIV

On 18 May 2018 WHO issued a statement on potential safety issue affecting women living with HIV using dolutegravir at the time of conception. Since then WHO headquarters, regional and country offices have been actively working with countries and partners, including civil society, to explore policy ...

The US Food and Drug Administration (FDA) and the European Medicines Agency's (EMA) are recommending new safety precautions for ViiV Healthcare's HIV drug dolutegravir.

Research has shown that the use of Dolutegravir as part of combination therapy results in fewer side effects and more effective suppression of viral load than any integrase inhibitors on the market.

ViiV Healthcare announced that the European Committee for Medicinal Products for Human Use (CHMP) has issued a Positive Opinion recommending marketing authorisation for Juluca (dolutegravir/rilpivirine) for the treatment of HIV infection in adults who are virologically suppressed (HIV-1 RNA less than 50 copies per mL) ...

FDA approved Juluca, the first complete treatment regimen containing only two drugs to treat certain adults with human immunodeficiency virus type 1 (HIV-1).

To compare the frequency and risk factors of toxicity-related treatment discontinuations between raltegravir and dolutegravir. Methods: All antiretroviral therapy (ART)-naïve and ART-experienced HIV-infected individuals from the Swiss HIV Cohort Study who initiated raltegravir or dolutegravir between 2006 and 2015 were investigated concerning treatment modification within the first ...

Introduction Pursuant to a license negotiated by the Medicines Patent Pool (MPP) with ViiV Healthcare (ViiV), an important new antiretroviral medicine, dolutegravir (DTG), will soon be available via generic competition in all low- and lower-middle-income countries, and a significant number of upper-middle-income countries as well. DTG ...