There are a number of things that can impact our immune system’s ability to eliminate a virus; the expression levels of particular proteins—specifically interferon proteins—is one of them. In the past, human type I interferons (IFNs), a large subgroup of interferon proteins, were thought to ...

The January issue of the Journal includes papers on a range of topics and reports from two recent meetings – the Ghent HIV Reservoir Characterization Symposium and the Third Biennial Strategies for an HIV Cure Meeting. To read an overview of the issue, click here. The January ...

Last month’s announcement that the Bill and Melinda Gates Foundation will give up to $140 million to a Boston drug device manufacturer to develop an implantable mini-pump to deliver drugs for pre-exposure prophylaxis (PrEP) against HIV infection has focused attention on the future of PrEP. ...

Washington, DC – January 13, 2017 – A clever new tuberculosis vaccine has shown promise in trials in mice. If it succeeds, it will be the first new TB vaccine in a century. With the rise of multidrug resistant tuberculosis, the difficulty of curing the ...

Eight weeks of treatment with AbbVie’s investigational, pan-genotypic, ribavirin-free regimen of glecaprevir/pibrentasvir (G/P) for chronic hepatitis C achieved high SVR rates in genotype 1 Japanese patients. – 99 percent (n=105/106) of genotype 1 (GT1) chronic HCV-infected Japanese patients without cirrhosis achieved SVR with 8 weeks of ...

In the context of its mandate expansion into tuberculosis, the Medicines Patent Pool (MPP) was asked by its funder, UNITAID, to conduct a study to examine how MPP licences could contribute to addressing some of the stewardship challenges for new drugs for tuberculosis, specifically for ...

People living with HIV often worry about whether HIV is accelerating the aging process. HIV itself isn’t making many people ill, but some people with HIV are having problems with heart disease, cancers and brittle bones. These conditions — typically experienced as people get older ...

A risk score based on routine assessments carried out during antenatal care in resource-limited settings can accurately predict which pregnant and breastfeeding women have an especially high risk of infection with HIV and would therefore benefit from pre-exposure prophylaxis (PrEP), investigators report in the online ...

Risk calculator developed by UCLA and Los Angeles LGBT Center may fill that void A new study from the UCLA Fielding School of Public Health suggests modifying federal health guidelines related to the use of pre-exposure prophylaxis to prevent HIV transmission because current standards could miss ...

Retroviruses – the family of viruses that includes HIV – are almost half a billion years old, according to new research by scientists at Oxford University. That’s several hundred million years older than previously thought and suggests retroviruses have ancient marine origins, having been with ...

TreatmentUpdate is CATIE’s flagship digest on cutting-edge developments in HIV and hepatitis C research and treatment. TreatmentUpdate 218: Research with women and HIV, December 2016 issue is available at: http://www.catie.ca/en/treatmentupdate/treatmentupdate-218 Original Article

Vemlidy® is the first new treatment for chronic hepatitis B infection to be approved in the European Union in nearly a decade Gilead Sciences, Inc. (Nasdaq: GILD) announced that the European Commission has granted marketing authorization for Vemlidy® (tenofovir alafenamide, TAF) 25 mg, a once-daily tablet ...

Antiviral therapy could be improved with the newly uncovered atomic-level details LA JOLLA—Salk Institute scientists have solved the atomic structure of a key piece of machinery that allows HIV to integrate into human host DNA and replicate in the body, which has eluded researchers for decades. ...

Study identifies characteristics of HIV-1 strains that mediate sexual transmission PHILADELPHIA – Upon sexual exposure, the AIDS virus must overcome some mighty barriers to find the right target cell and establish a new infection. It must traverse the genital mucosa and squeeze through tightly packed epithelial ...

Smoking “dramatically” increases the risk of pregnancy loss – miscarriage or stillbirth – in HIV-positive women, US investigators report in the online edition of AIDS. Researchers from the large Women’s Interagency HIV Study (WIHS) examined the impact of smoking on pregnancy loss in HIV-positive and ...

CytoDyn Inc. (OTC.QB:CYDY), a biotechnology company focused on the development of new therapies for combating human immunodeficiency virus (HIV) infection, today announced the Company filed a request for Breakthrough Therapy Designation with the FDA for PRO 140 as a treatment for HIV-1 infection in treatment-experienced ...

Patients with hepatitis C virus infection who received an antiviral drug around the time they underwent liver transplantation saw a high rate of sustained virologic response, according to a Northwestern Medicine phase II clinical trial. The finding suggests that the therapy might be an effective ...

ELPA presents the stark findings of the 2016 Hep-CORE Report Berlin, 20 December 2016 – Fifty-two per cent (52%) of surveyed European (25) and Mediterranean Basin (2) countries lack national strategies to address viral hepatitis B or C despite the WHO World Health Assembly resolution calling ...