Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV

Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents Living with HIV

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Antiretroviral therapy (ART) for the treatment of HIV infection has improved steadily since the advent of potent combination therapy in 1996. ART has dramatically reduced HIV-associated morbidity and mortality and has transformed HIV infection into a manageable chronic condition. In addition, ART is highly effective ...

Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents.

Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents.

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Revisions to the April 8, 2015, version of the guidelines are largely based on findings from two large, randomized controlled trials that addressed the optimal time to initiate antiretroviral therapy (ART)—START (Strategic Timing of Antiretroviral Therapy) and TEMPRANO. Both studies demonstrated approximately a 50% reduction ...